What
is the Female HPV Study?
The Female HPV study, funded by the National Cancer Institute, involves
studying Human papillomaviruses (HPVs) among women in Hawai'i. The study
will identify factors that affect an HPV infection and may increase the
risk of developing cervical cancer, such as the kinds of foods you eat
and your immune characteristics. The Principal Investigator is Marc
T Goodman, Ph.D.
Who
is eligible to participate in the HPV Partner Study?
You may qualify for this study if you are female, at least 18 years
of age, not currently pregnant or at least 6 months post-partum, have
been sexually active within the past 6 months, have not had a hysterectomy,
have not had surgery for abnormal pap smear within the past 18 months,
not immune-compromised (e.g., transplant recipient, HIV-positive, or
within 6 months cancer chemotherapy), no history of blood-clotting disorders,
and plan to reside on Oahu two years or more. Women do not have to be
infected with HPV to participate in the study.
What does
this study involve?
The first study visit will take about 1 1/2 hours. You may be asked
to return for follow up study visits which will take about 1 hour; if
so, you will be asked to come for up to 15 visits over a period of 5
years. At each visit you will have a Pap smear and samples (swabs, brushes
or washes) taken of your cervix, vulva, and vaginal walls to test for
pH level, inflammatory cells, infection with HPV, Chlamydia trachomatis,
Neisseria gonorrhea, and herpes simplex virus, and to measure small proteins
called cytokines that help fight off infection. At each visit the study
clinician will also take a sample (swabbing) of your hand, mouth and,
if you choose, of your anal-rectal region to look for infection with
HPV. A fasting blood sample will be taken to measure nutrients and you
will be asked questions about yourself and your lifestyle.
What will
a participant receive from the HPV Study?
You will receive free Pap tests, free HPV testing, a free diet analysis,
free parking, and $40 compensation for time and travel. The study will
not provide or pay for any treatment.