Ramos Home Page

Our mission is to understand the regulation of cell signaling pathways. We are particularly focused on the function of PEA-15 and its homologues in the MAP kinase and apoptotic signal transduction pathways. Because of the fundamental nature of this work it has applications to a number of pathological states including breast cancer, diabetes, brain cancer and leukemia.

Funding for our research is provided by The National Institutes of Health, the Department of Defense, the Hawaii Community Foundation and the Friends of the Cancer Research Center. Here you can get acquainted with our work through our publications and statement of research interests. In addition, take a moment to note who is in the lab and some of our collaborators. Our lab is on the beautiful island of Oahu and you can find directions to us here.
Thanks for visiting!

E-mail: jramos@crch.hawaii.edu
COS: http://myprofile.cos.com/jramos

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NEWS

Read our paper in PNAS suggesting that PEA-15 acts as a scaffold for ERK activation of RSK2.		CONGRATULATIONS! to John on successful completion of his Ph.D.!
Read our review from CMLS of DED-containing proteins here.		We welcome our summer students Justine, Kristen and Sam.
Read our review from IJBCB on the regulation of ERK signaling here.		Take a pictorial tour of our lab facilities. (pps, web)
Learn about PEA-15 at our UCSD-Nature Molecule page.		New work on PEA-15 and RSK2 listed at NLM's Pubmed.
	Join our team! (pdf)

"The first principle (of scientific integrity) is that you must not fool yourself-and you are the easiest person to fool..."- Richard P. Feynman, The Pleasure of Finding Things Out, p.212 (1999).