Our
mission is to understand the regulation of cell
signaling pathways. We are particularly focused on the
function of
PEA-15 and its
homologues in the MAP kinase and
apoptotic signal transduction pathways. Because of the fundamental nature of this
work it has applications to a number of pathological states
including breast cancer, diabetes, brain cancer and leukemia.
"The
first principle (of scientific integrity) is that you must not fool
yourself-and you are the easiest person to fool..."- Richard P. Feynman, The Pleasure of Finding Things Out,
p.212 (1999).