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University of Hawai'i Cancer Center

Cancer Biology Program

University of Hawai'i at Manoa
651 ILALO Street, BSB Room 241C 
Honolulu, Hawai'i  96813

Office: (808) 564-5843 Lab: (808) 440-5236

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joeOur mission is to understand the underlying mechanisms that control cancer cell proliferation and invasion. We are particularly focused on the role of PEA-15 and the ERK MAP kinase pathway in these aspects of cancer formation and progression.  In collaboration with Chemists in the Natural Products and Cancer Biology program we are developing new drugs to target cancer based on our basic research findings. Currently we are investigating the dysregulation of cell signalling in neuroblastoma and glioblastoma.

Funding for our research is provided by The National Institutes of Health, the Department of Defense, the Hawaii Community Foundation and the Friends of the Cancer Research Center. Here you can get acquainted with our work through our publications and statement of research interests.  In addition, take a moment to note who is in the lab and some of our collaborators. Our lab is on the beautiful island of Oahu and you can find directions to us here. Thanks for visiting!

mailE-mail: jramos@cc.hawaii.edu
COS:   http://myprofile.cos.com/jramos
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NEWS

Florian has a new paper in Oncogene on PEA-15 in tumorigenesis. In the context of oncogenic Ras, PEA-15 activates PLD and enhances transformation.

lab folk
Congratulations to Maisel for his award winning confocal micrograph in the ATCC photo contest! He took 1st place in the popular vote!
Read our paper in IJC on the suppression of neuroblastoma metastasis by PEA-15. We welcome Chena, Meike and Martin to the lab! And Anna for her rotation!
Read our paper in FASEB J on negative regulation of T-cell activation by PEA-15. Behold! The New Cancer Center Building!
Take a pictorial tour of our current lab facilities. (pps, web).
See three recent papers with our collaborators Dr. Nixon on PEA-15, Dr. Williams on Stictamides and Dr. Matter on Bit1. See new work on PEA-15 and RSK2 listed at NLM's Pubmed. Learn more about PEA-15 at our UCSD-Nature Molecule page.
   

Quote

"The first principle (of scientific integrity) is that you must not fool yourself-and you are the easiest person to fool..."- Richard P. Feynman, The Pleasure of Finding Things Out.

 

Web page created and maintained by Joe W. Ramos

Revised: January 2012

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