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Cancer Research Center of Hawai'i

Natural Products and Cancer Biology Program

University of Hawai'i at Manoa
651 ILALO STREET, BSB Room 241C 
Honolulu, Hawai'i  96813

Office: (808) 564-5843  Lab: (808) 440-5236

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Our mission is to understand the regulation of cell signaling pathways.  We are particularly focused on the function of PEA-15 and its homologues in the MAP kinase and apoptotic signal transduction pathways.  Because of the fundamental nature of this work it has applications to a number of pathological states including breast cancer, diabetes, brain cancer and leukemia.

Funding for our research is currently provided by The National Institutes of Health, the D.O.D, the Hawaii Community Foundation and the Friends of the Cancer Research Center. We hope you take the time to get acquainted with our work through our publications and statement of research interests.  In addition, take a moment to note who is in the lab and some of our collaborators. Our lab is on the beautiful island of Oahu and you can find directions to us here.
Thanks for visiting!

mailE-mail: jramos@crch.hawaii.edu
COS:  http://myprofile.cos.com/jramos

Lab News

 

See our paper in PNAS suggesting that PEA-15 acts as a scaffold for ERK activation of RSK2. We welcome Jesse to the lab for his graduate rotation.
Read our new review from IJBCB on the regulation of ERK signaling here. Join our lab!  We are currently looking for ambitious postdocs to join our team. Flyer (pdf)
Learn about PEA-15 at our UCSD-Nature Molecule page. Take a pictorial tour of our lab facilities in Kaka'ako. (pps, web)
PEA-15 sounds like this.  See gene2music. Ramos Lab
Honolulu
New work on PEA-15 listed at NLM's Pubmed.

Quote

"The first principle (of scientific integrity) is that you must not fool yourself-and you are the easiest person to fool..."- Richard P. Feynman, The Pleasure of Finding Things Out, p.212 (1999).

Web page created and maintained by Joe W. Ramos

Revised 11 September 2008

© 2006, Cancer Research Center of Hawaii. All rights reserved.