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A Metaphor for Cell Signaling:  The milkman is the signal
From Genes and the Biology of Cancer, Varmus and Weinberg, 1993, Scientific American Library

 

Molecular Biology of the Cell I:

CMB 621, Rm. T-208, Biosciences Bldg, Tu & Th, 3:30 to 5:30 PM

(text: Molecular Biology of the Cell 4th  by Alberts et al.)

Signal Transduction I: G-Protein Coupled Receptors (Chp 15)- Dec. 2
Signal Transduction II: Receptor Tyrosine Kinases (Chp 15)- Dec 4

Signal Transduction III: Apoptosis (Chp 15, reviews)- Dec 9

Lecture Notes
 
The following material may also be useful:
Molecular Cell Biology by Lodish et al.
N. Mochizuki, et al.  Nature 411:1065-1068  = FRET analysis of Ras activation. 
Strasser, O' Connor, and Dixit,  Annu. Rev. Biochem.  69:217–45 =Apoptosis Signaling Review
P. H. Krammer. Nature 407:789-795 =Review of Fas activation of apoptosis  
 
Molecular and Cellular Biology of Cancer:
CMB 654C, Fall & Spring, BSB 222N, Friday 11:00-12:00PM
Class Web Site is here.
 
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