Publications

(1993-1997)  (1998-2000)  (2001-2003
(2004-2005)  (2006-2008)

  S. Pastorino and J.W. Ramos. (2008). Glioma: Challenges and new insights in the development of effective therapies.
Hawaii Medical Journal.
67:20-23.    PDF

 H. Vaidyanathan, J. Opoku-Ansah, S. Pastorino, H. Renganathan, M.L. Matter, and J.W. Ramos. (2007). ERK MAP kinase is targeted to RSK2 by the phosphoprotein PEA-15.
PNAS.
104(50): 19837-19842.          PDF

  F. Renault-Mihara, F. Beuvon, X. Iturrioz, B. Canton, S. De Bouard, N. Léonard, S. Mouhamad, A. Sharif, J.W. Ramos, M-P. Junier, and H Chneiweiss.  (2006). PEA-15 Expression Inhibits Astrocyte Migration by a PKC Delta-Dependent Mechanism.   
Mol. Biol. Cell
, 17(12):5141-52.         PDF

   M.L. Matter and J.W. Ramos.  (2006).  Expression cloning of signaling proteins regulated by cell adhesion. 
Methods in Molecular Biology, vol. 341: Cell-Cell Interactions: Methods and Protocols
.  Sean P. Colgan ed., Humana Press Inc, Totowa, NJ.

  H. Renganathan, H. Vaidyanathan, A. Knapinska and J.W. Ramos. (2005). Phosphorylation of PEA-15 Switches its Binding Specificity from ERK MAP kinase to FADD. 
Biochem J.
390(3):729-735.               PDF

  J.W. Ramos. (2005). PEA-15 Phosphoprotein: a potential cancer drug target.
Hawaii Medical Journal.
64:77-79.    PDF

  R. Sur and J.W. Ramos. (2005). Vanishin is a novel ubiquitinylated death effector domain protein that blocks ERK activation. 
Biochem J.
387(2):315-324.               PDF

F-L. Chou, J. M. Hill, J-C. Hsieh, J. Pouyssegur, A. Brunet, A. Glading, F. Überall, J.W. Ramos, M.H. Werner, and M.H. Ginsberg.  (2003).  PEA-15 binding to ERK1/2 MAP kinases is required for its modulation of integrin activation. 
J. Biol. Chem
.  278(52):52587-52597.                                                                 PDF

H. Vaidyanathan and J.W. Ramos.  (2003).  Rsk2 activity is regulated by its association with PEA-15. 
J. Biol. Chem
.  278(34):32367-32372.                                                                 PDF

  J.M. Hill, H. Vaidyanathan, J.W. Ramos, M.H. Ginsberg and M.H. Werner.  (2002).  Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain. 
EMBO J  21(23):
6494-6504.              PDF

  J.W. Ramos and M.H. Ginsberg.  (2002).  Expression cloning strategies for the identification of adhesion molecules. 
Methods in Cell-matrix adhesion
.  Josephine Adams ed., Academic Press.

  M.L. Matter, M.H. Ginsberg, and J.W. Ramos. (2001).  Identification of cell signaling molecules by expression cloning. 
Science's STKE   

  J.W. Ramos*, E. Formstecher*, M. Fauquet, D.A. Calderwood, J-C. Hsieh, B. Canton, X-T. Nguyen, J-V. Barnier, J. Camonis,  M.H. Ginsberg, and H. Chneiweiss (2001).  PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase.  *Co-first authors.    
Developmental Cell 1:
239-250.         PDF

  Y. Zhang, O. Redina, Y.M. Altshuller, M. Yamazaki, J. Ramos, H. Chneiweiss, Y. Kanaho, M.A. Frohman (2000). Regulation of PLD1 and PLD2 expression levels by PEA-15, a novel PLD-interacting protein.
J.Biol.Chem. 275
:35224-35232.        PDF

  J.W. Ramos, P.E. Hughes, M.W. Renshaw, H. Chneiweiss, and M.H. Ginsberg (2000).  The Death Effector Domain Protein, PEA-15, potentiates Ras activation of ERK by an adhesion independent mechanism. 
Mol.Biol.Cell.
11:2863-72.                  PDF

  C.A. Fenczik, J.W. Ramos, and M.H. Ginsberg.  (1999).  Expression cloning of proteins that modify integrin activation. 
Signaling Through Cell Adhesion Molecules
.  Jun-Lin Guan ed., CRC Press, pgs. 235-243.
  J.W. Ramos, T.J. Kojima, P.E. Hughes, C.A. Fenczik, and M.H. Ginsberg. (1998).  The Death Effector Domain of PEA-15 is involved in its regulation of integrin activation.
J. Biol. Chem.
273:33897-33900.      PDF
  C.A. Fenczik, T. Sethi, J.W. Ramos, P.E. Hughes, and M.H. Ginsberg. (1997).  Complementation of dominant suppression implicates CD98 in integrin activation. 
Nature 390
:81-85.                                PDF
  J.W. Ramos, C.A. Whittaker, and D.W. DeSimone. (1996). Integrin-dependent adhesive activity is spatially controlled by inductive signals at gastrulation. 
Development  122
:2873-2883.          PDF
  J.W. Ramos and D.W. DeSimone. (1996). Xenopus embryonic cell adhesion to fibronectin: position-specific activation of RGD/synergy-site-dependent migratory behavior at gastrulation.
J. Cell Biology
134:227-240.              PDF
  D. Alfandari,  J. Ramos, L. Clavilier, D.W. DeSimone, and T. Darribere. (1996).  The RGD-dependent and Hep II binding domains of fibronectin govern the adhesive behavior of amphibian embryonic cells. 
Mech. of Development.
  56:83-92.    PDF
  K. Danker, H. Hacke, J. Ramos, D.W. DeSimone, and D. Wedlich. (1993). V+ Fibronectin expression and localization prior to gastrulation in Xenopus laevis embryos.
Mech. of Development 44
:155-165.
 

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© 2006, Joe W. Ramos