The Biostatistics
Shared Resource (BSR) provides statistical consultation and support
to the research enterprise of the Center Research Center of Hawaii.
The primary goal of the resource is to improve the quality of the
research through sound statistical principles. The resource was established
in 1995 and provides access to statistical support to all Center
members on all aspects of research. The BSR provides short-term as
well as long-term support for research projects. Support is provided
to scientists in epidemiology, health behavior and quality of life
research, and molecular and clinical oncology. The members of the
Shared Resource often serve as co-investigators on epidemiology and
cancer prevention and control projects. Consultation is available
in the following areas: design, data collection, data analysis, statistical
programming, interpretation and dissemination of results, and protocol
review. The members of the resource have contributed to the publication
of many peer-reviewed manuscripts from Center research projects.
In addition,
the statisticians work on methodological issues important to the
research ongoing at CRCH. One area of interest is measurement error
models that correct for bias in model parameter estimates when the
exposure variable is measured with error. The role of dietary intake
and sunlight exposure in cancer etiology are of interest at the Center,
and these variables are measured with error. Another interest is
in how susceptibility genes affect cancer risk, in combination with
exposure data. Therefore, statistical techniques for the investigation
of genes and lifestyle-gene interactions in cancer models are also
studied.
From July 2001 to June 2004, the Shared Resource was funded by fourteen
investigators through forty-seven grants. The Cancer Center Core grant
allows for all CRCH member scientists to have access to the Shared
Resource for short-term statistical consultation. The Shared Resource
is only available to Cancer Research Center of Hawai‘i members.
A chargeback system exists that easily allows for support of short-term
projects.
Leo Wang-Kit
Cheung, Ph.D.
John Grove, M.S., Ph.D.
Ian Pagano, Ph.D.
Alana Steffen, Ph.D.
Judith Tom, M.S.
Lucy Liu Shen, M.S.
Amy Krambrink, M.S.
Kami White, M.S.
Andrew Williams, M.A.