List of Ongoing Clinical Trials: Patient Summary

GOG-0219
Phase III Randomized Study of Cisplatin and Radiotherapy With Versus Without Tirapazamine in Patients With Stage IB, IIA, IIB, IIIB, or IVA Carcinoma of the Cervix

Summary

Drugs uused in chemotherapy, such as cisplatin and tirapazamine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Internal radiation uses radioactive material placed directly into or near a tumor to kill tumor cells. Cisplatin and tirapazamine may make tumor cells more sensitive to radiation therapy. It is not yet known whether giving cisplatin together with radiation therapy is more effective with or without tirapazamine in treating cervical cancer.

This randomized phase III trial is studying cisplatin, radiation therapy, and tirapazamine to see how well they work compared to cisplatin and radiation therapy in treating patients with cervical cancer.

Consent Form for Patients | Fast Fact Sheet