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List of Ongoing Clinical Trials: Patient Summary

NSABP Protocol B-42
Phase III Randomized Study of Letrozole in Postmenopausal Women With Hormone Receptor-Positive Breast Cancer Who Have Completed Adjuvant Hormonal Therapy Comprising An Aromatase Inhibitor and/or Tamoxifen Citrate

Summary
Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer by lowering the amount of estrogen the body makes. It is not yet known whether letrozole is more effective than a placebo in treating patients with hormone receptor-positive breast cancer.

This randomized phase III trial is studying letrozole to see how well it works compared with a placebo in treating postmenopausal women who have received hormone therapy for hormone receptor-positive breast cancer.

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