Brian Issell, M.D.

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Cancer Research Center of Hawaii

Brian F. Issell, M.D.
Professor (Researcher), Cancer Research Center of Hawaii;
Professor of Medicine, John A. Burns School of Medicine
M.B., Ch.B. (M.D.) University of Otago School of Medicine, New Zealand;
Practicing Internist and Medical Oncologist;
Fellow, Royal Australasian College of Physicians;
Fellow, American College of Physicians;
Diplomate of American Board of Internal Medicine in Internal Medicine and Medical Oncology
brian@crch.hawaii.edu

Publication list via PubMed
Dr. Issell's personal research is directed towards discovering better ways to treat and rehabilitate cancer patients. His most recent work focuses on developing a Complementary and Alternative Medicine initiative that evaluates traditional practices of Hawaii's multicultural population including the use of botanicals for the control of cancer and its related symptoms. He is conducting a Phase I study of Noni that is supported by a National Institutes of Health R21 grant as a first step in the initiative. A recently completed RO1-supported project prospectively examined treatment patterns for women diagnosed with breast cancer in an effort to understand why certain ethnic groups such as Native Hawaiians and Filipinos experience a worse survival.
Administratively, Dr. Issell directs the Cancer Research Center's Clinical Trials Unit. He is principal investigator of the National Cancer Institute - supported, Cancer Information Service of Hawaii and the Hawaii Minority - Based Community Clinical Oncology Program for conducting clinical trials. As a practicing medical oncologist, Dr. Issell is a teaching attending on the Queen Emma Clinics Service at the Queens Medical Center.

Selected Publications
Matsunaga, D.S.; Enos, R.; Gotay, C.C.; Banner, R.O.; DeCambra, H.; Hammond, O.W.; Hedlund, N.; Ilaban, E.K.; Issell, B.F.; Tsark, J.A. Participatory Research in a Native Hawaiian Community: The Waianae Cancer Research Project. Cancer, 78: 1582-1586, 1996.
Rinehart, J.; Hersch, E.; Issell, B.F.; Triozzi, P.; Buhles, W.: Phase I Trial of Recombinant Human Interleukin 1(Rh 1L-1), Carboplatin and Etoposide in Patients with Solid Cancers, Cancer Investigation 5: 403-410. 1997.
Gotay, C.C.; Hara, W; Issell, B.F.; Maskarinec, G.: Use of Complementary and Alternative Medicine in Hawaii Cancer Patients: Hawaii Medical Journal, 58: 94-98, 1999.
Gotay, C.C.: Banner, R.O.; Matsunaga, D.S.;Hedlund, N.; Enos, R.;Issell, B.F.; De Cambra, H.: Impact of a Culturally Appropriate Intervention on Breast and Cervical Screening among Native Hawaiian Women, Preventive Medicine 31, 529-537, 2000.
Maskarinec G, Pagano I, Yamashiro G, Issell BF.: Influences of Ethnicity, Treatment, and Comorbidity on Breast Cancer Survival. Journal of Clinical Epidemiology 56, 678-685, 2003.
Issell, B. F., Maskarinec, G., Pagano, I., Gotay, C. C. Breast Cancer Treatment among Women of Different Ethnicity in Hawaii. Cancer Investigation , In Press, 2004.
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